SKILLEMALL.ai
GitHub ↗ RU Sign in

BC ligandmpnn

Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use proteinmpnn. For solubility optimization, use solublempnn.

FreedomIntelligence/OpenClaw-Medical-Skills Hermes author: FreedomIntelligence 1 file body ≈ 981 tokens Open the sourcegithub.com↗ analyzed 14 h ago

Ligand-aware protein sequence design using LigandMPNN.

As a process C 54/100 · Has gaps — References files that are not bundled: ../../docs/installation.md

ProcedureDesigntype and topics are labelled automatically from the skill text
Runs in: Hermes Agent
JSON
Technical rating
B
90/100
safety, quality, tests
Safety 60%
100
Quality 40%
75
Run on models
none yet
Process rating
C
54/100
Has gaps
References files that are not bundled: ../../docs/installation.md
Tools and files w 18
0
Progress reporting w 2
0
When it triggers w 12
20
the three weakest of ten parameters · all ten

How to improve

  1. For Hermes the description must be one sentence under 60 characters; move the conditions to a "When to Use" section.
  2. The text references files that are not there: add them or drop the references.
For the model run — optional
  • Your own cases (evals/evals.json, 4–6 real requests with expected answers): the full check would then run those instead of a model-drafted suite.
  • A spec.yaml with trigger phrases and assertions — a behaviour contract for CI; `skilltest init` writes a template.

Guard findings · 0

✓ No critical or high findings

Files scanned: 1. Evidence is masked. Grey chips explain why severity was lowered.

Against the Agent Skills spec

  • warning description-long-hermes description is 354 chars; the Hermes authoring standard requires ≤ 60 (one sentence, ending with a period)
  • warning missing-ref reference to a missing file: ../../docs/installation.md
  • note frontmatter-key unknown frontmatter key "biomodals_script"

Process rating: all ten parameters 54/100

Will not run. References files that are not bundled: ../../docs/installation.md
  • 0Tools and files. 1 referenced file(s) missing: ../../docs/installation.md
  • 0Progress reporting. Says nothing while it works
  • 20When it triggers. No condition that starts the skill
  • 50Failures and branches. 0 branches, has a failure section
  • 60Result and completion. Output format stated, no completion criterion
  • 70Inputs and preconditions. Inputs and preconditions are listed
  • 85Steps. 7 steps, 1 vague phrases
  • 100Consistency. Name and required fields are in place
  • 100Execution cost. Instruction body is 981 tokens
  • 100Running it twice. No mutating operations
  • low 10 top-level sections: this looks like several domains in one skill

Everything here is measured from the skill text rather than judged by a model, so the numbers are checkable. A parameter weighs more when it is a more common reason for the process to stall.

Quality signals

  • +5Description has no quoted example phrases that should trigger the skill
  • +4Description does not say when NOT to use the skill (false activations)
  • +2Single-language instructions
  • +3Description length 353: enough signal without eating the budget
  • +4Structure: 17 headings
  • +3Step-by-step instructions: 7 items
  • +3Output format is stated explicitly
  • +4Has examples (7 code blocks)
  • +1License stated

Quality base 70; lint remarks subtract, signals add up to 100. Result: 75.