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BC solublempnn

Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design, use proteinmpnn. For ligand-aware design, use ligandmpnn.

FreedomIntelligence/OpenClaw-Medical-Skills Hermes author: FreedomIntelligence 1 file body ≈ 957 tokens Open the sourcegithub.com↗ analyzed 14 h ago

Solubility-optimized protein sequence design using SolubleMPNN.

As a process C 50/100 · Has gaps — References files that are not bundled: ../../docs/installation.md

ReferenceDesigntype and topics are labelled automatically from the skill text
Runs in: Hermes Agent
JSON
Technical rating
B
90/100
safety, quality, tests
Safety 60%
100
Quality 40%
75
Run on models
none yet
Process rating
C
50/100
Has gaps
References files that are not bundled: ../../docs/installation.md
Tools and files w 18
0
Progress reporting w 2
0
When it triggers w 12
20
the three weakest of ten parameters · all ten

How to improve

  1. For Hermes the description must be one sentence under 60 characters; move the conditions to a "When to Use" section.
  2. The text references files that are not there: add them or drop the references.
For the model run — optional
  • Your own cases (evals/evals.json, 4–6 real requests with expected answers): the full check would then run those instead of a model-drafted suite.
  • A spec.yaml with trigger phrases and assertions — a behaviour contract for CI; `skilltest init` writes a template.

Guard findings · 0

✓ No critical or high findings

Files scanned: 1. Evidence is masked. Grey chips explain why severity was lowered.

Against the Agent Skills spec

  • warning description-long-hermes description is 358 chars; the Hermes authoring standard requires ≤ 60 (one sentence, ending with a period)
  • warning missing-ref reference to a missing file: ../../docs/installation.md
  • note frontmatter-key unknown frontmatter key "biomodals_script"

Process rating: all ten parameters 50/100

Will not run. References files that are not bundled: ../../docs/installation.md
  • 0Tools and files. 1 referenced file(s) missing: ../../docs/installation.md
  • 0Progress reporting. Says nothing while it works
  • 20When it triggers. No condition that starts the skill
  • 30Running it twice. 1 mutating operations with no state check
  • 50Failures and branches. 0 branches, has a failure section
  • 60Result and completion. Output format stated, no completion criterion
  • 70Inputs and preconditions. Inputs and preconditions are listed
  • 75Steps. 3 steps
  • 100Consistency. Name and required fields are in place
  • 100Execution cost. Instruction body is 957 tokens
  • low 10 top-level sections: this looks like several domains in one skill

Everything here is measured from the skill text rather than judged by a model, so the numbers are checkable. A parameter weighs more when it is a more common reason for the process to stall.

Quality signals

  • +5Description has no quoted example phrases that should trigger the skill
  • +4Description does not say when NOT to use the skill (false activations)
  • +2Single-language instructions
  • +3Description length 357: enough signal without eating the budget
  • +4Structure: 15 headings
  • +3Step-by-step instructions: 3 items
  • +3Output format is stated explicitly
  • +4Has examples (6 code blocks)
  • +1License stated

Quality base 70; lint remarks subtract, signals add up to 100. Result: 75.