SKILLEMALL.ai

CB alphagenome

Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq, DNase, ATAC, ChIP-TF, ChIP-histone, CAGE, PRO-cap, splicing, polyadenylation and contact-map tracks), scores variants or scans windows on demand with the AlphaGenome model for human and mouse (variant scoring, in silico mutagenesis, REF-versus-ALT track prediction), and builds Atlas website deep links. Use when the user mentions AlphaGenome, AlphaGenome Atlas, AVI or AlphaGenome Variant Impact, DeepMind variant effect prediction, or wants to prioritise or mechanistically interpret non-coding, regulatory, splicing, enhancer, promoter, or chromatin-accessibility effects of SNVs from a VCF, credible set, or region. Research use only; not a clinical tool.

K-Dense-AI/claude-scientific-skills Agent Skills author: K-Dense-AI MIT 8 files · 4 scripts body ≈ 3 934 tokens Open the sourcegithub.com↗ analyzed 12 h ago

Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and…

As a process B 67/100 · Nearly there — weak spots: result and completion, inputs and preconditions, running it twice

ProcedureSoftware developmentSales and CRMtype and topics are labelled automatically from the skill text
JSON
Technical rating
C
88/100
safety, quality, tests
Safety 60%
95
Quality 40%
78
Run on models
none yet
Process rating
B
67/100
Nearly there
Result and completion w 14
0
Inputs and preconditions w 11
0
Running it twice w 4
30
the three weakest of ten parameters · all ten

What is at stake

Medium-severity findings: the skill is probably honest, but read what alarmed the scanner.

Broad scope medium severity

Below is the worst case for this category. The finding here is medium: the guard saw a sign, not a proof.

If you install

The skill asks for more than the task needs: broad tool access, credential environment variables, binaries. Every extra permission widens the damage from a mistake or a compromise.

For the author

Narrow allowed-tools and the variable list to the minimum; replace binaries with readable sources or scripts.

How to improve

    For the model run — optional
    • Your own cases (evals/evals.json, 4–6 real requests with expected answers): the full check would then run those instead of a model-drafted suite.
    • A spec.yaml with trigger phrases and assertions — a behaviour contract for CI; `skilltest init` writes a template.

    Guard findings · 1

    ✓ No critical or high findings

    Medium and low: 1
    • medium Broad scope meta-broad-allowed-tools SKILL.md:1
      Broad tool permissions pre-approved: Bash
      allowed-tools: Read Write Edit Bash

    Files scanned: 8. Evidence is masked. Grey chips explain why severity was lowered.

    Against the Agent Skills spec

    ✓ No remarks against the Agent Skills spec

    Process rating: all ten parameters 67/100

    • 0Result and completion. Does not say what the result is
    • 0Inputs and preconditions. Does not say what the process needs to start
    • 30Running it twice. 4 mutating operations with no state check
    • 50Failures and branches. 0 branches, has a failure section
    • 100Tools and files. Tools declared in frontmatter
    • 100Steps. 13 steps
    • 100When it triggers. States when to use and when not to
    • 100Consistency. Name and required fields are in place
    • 100Execution cost. Instruction body is 3934 tokens
    • 100Progress reporting. Reports progress
    • medium Safety rules and hard prohibitions inside a skill: they belong in the system prompt, here they protect nothing

    Everything here is measured from the skill text rather than judged by a model, so the numbers are checkable. A parameter weighs more when it is a more common reason for the process to stall.

    Quality signals

    • +5Description has no quoted example phrases that should trigger the skill
    • +4Description does not say when NOT to use the skill (false activations)
    • +3Description length 845: 120–800 characters recommended
    • +3Output format is not stated: the model decides each time
    • -5TODO / placeholder text left in the skill
    • -31 of 4 scripts are never mentioned in SKILL.md
    • +2Single-language instructions
    • +4Structure: 16 headings
    • +3Step-by-step instructions: 13 items
    • +4Has examples (8 code blocks)
    • +4Reference files are cited in the instructions (3 of 3)
    • +1License stated

    Quality base 70; lint remarks subtract, signals add up to 100. Result: 78.