AA mr-scrna-research-planner
Generates complete Mendelian Randomization + single-cell transcriptomics (scRNA-seq) research designs from a user-provided direction. Always use this skill whenever a user wants to design, plan, or build a study combining MR and single-cell data — even if phrased as "help me write a paper on X", "design a bioinformatics study for Y", or "I want to study Z using MR and scRNA". Covers five study patterns (mechanism gene-set, key-cell, candidate-gene reverse validation, exposure-disease-cell triangulation, translational biomarker) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, and publication upgrade path.
As a process A 81/100 · Runs to the end — weak spots: result and completion, progress reporting
How to improve
- Your own cases (evals/evals.json, 4–6 real requests with expected answers): the full check would then run those instead of a model-drafted suite.
- A spec.yaml with trigger phrases and assertions — a behaviour contract for CI; `skilltest init` writes a template.
Guard findings · 0
✓ No critical or high findings
Files scanned: 9. Evidence is masked. Grey chips explain why severity was lowered.
Against the Agent Skills spec
- note
frontmatter-keyunknown frontmatter key "skill-author"
Process rating: all ten parameters 81/100
- 0Result and completion. Does not say what the result is
- 0Progress reporting. Says nothing while it works
- 70Inputs and preconditions. Inputs and preconditions are listed
- 100Tools and files. No external tools needed
- 100Steps. 27 steps
- 100When it triggers. States when to use and when not to
- 100Failures and branches. 2 branches, has a failure section
- 100Consistency. Name and required fields are in place
- 100Execution cost. Instruction body is 1803 tokens
- 100Running it twice. No mutating operations
- medium Safety rules and hard prohibitions inside a skill: they belong in the system prompt, here they protect nothing
Everything here is measured from the skill text rather than judged by a model, so the numbers are checkable. A parameter weighs more when it is a more common reason for the process to stall.
Quality signals
- +4Description does not say when NOT to use the skill (false activations)
- +3Output format is not stated: the model decides each time
- +4No input/output examples
- +2Single-language instructions
- +5Description quotes 3 example trigger phrases
- +3Description length 765: enough signal without eating the budget
- +4Structure: 11 headings
- +3Step-by-step instructions: 27 items
- +4Reference files are cited in the instructions (7 of 7)
- +1License stated
Quality base 70; lint remarks subtract, signals add up to 100. Result: 89.