SKILLEMALL.ai

AC prioritize-drug-targets-ls

Generate and prioritize experimentally testable target hypotheses from one or more small-molecule structures. Use when a user supplies SMILES or a compound library and asks which targets the molecules may modulate, how structural neighbors and SAR support the hypotheses, which biological and competitive evidence should be checked, or which compounds and targets should advance to orthogonal validation.

ClawHub Agent Skills author: yuanzhian-patsnap v1.0.0 MIT-0 2 files body ≈ 4 565 tokens Open the sourceclawhub.ai analyzed 3 d ago

Generate and prioritize experimentally testable target hypotheses from one or more small-molecule structures.

As a process C 57/100 · Has gaps — weak spots: result and completion, inputs and preconditions, running it twice

GeneratorInfrastructureResearchtype and topics are labelled automatically from the skill text
JSON
Technical rating
A
95/100
safety, quality, tests
Safety 60%
100
Quality 40%
87
Run on models
none yet
Process rating
C
57/100
Has gaps
Result and completion w 14
0
Inputs and preconditions w 11
0
Running it twice w 4
30
the three weakest of ten parameters · all ten

How to improve

    For the model run — optional
    • Your own cases (evals/evals.json, 4–6 real requests with expected answers): the full check would then run those instead of a model-drafted suite.
    • A spec.yaml with trigger phrases and assertions — a behaviour contract for CI; `skilltest init` writes a template.

    Guard findings · 0

    ✓ No critical or high findings

    Files scanned: 2. Evidence is masked. Grey chips explain why severity was lowered.

    Against the Agent Skills spec

    • note frontmatter-key unknown frontmatter key "copyright"

    Process rating: all ten parameters 57/100

    • 0Result and completion. Does not say what the result is
    • 0Inputs and preconditions. Does not say what the process needs to start
    • 30Running it twice. 2 mutating operations with no state check
    • 50When it triggers. No condition that starts the skill
    • 50Failures and branches. 0 branches, has a failure section
    • 70Execution cost. Instruction body is 4565 tokens
    • 85Steps. 185 steps, 1 vague phrases
    • 100Tools and files. No external tools needed
    • 100Consistency. Name and required fields are in place
    • 100Progress reporting. Reports progress
    • medium Safety rules and hard prohibitions inside a skill: they belong in the system prompt, here they protect nothing
    • low 19 top-level sections: this looks like several domains in one skill

    Everything here is measured from the skill text rather than judged by a model, so the numbers are checkable. A parameter weighs more when it is a more common reason for the process to stall.

    Quality signals

    • +5Description has no quoted example phrases that should trigger the skill
    • +3Output format is not stated: the model decides each time
    • +1No license
    • +2Single-language instructions
    • +4Description says when NOT to use the skill
    • +3Description length 404: enough signal without eating the budget
    • +4Structure: 41 headings
    • +3Step-by-step instructions: 185 items
    • +4Has examples (0 code blocks)

    Quality base 70; lint remarks subtract, signals add up to 100. Result: 87.

    External checks

    ClawHub: clean
    This skill is a disclosed scientific workflow for drug-target hypothesis research and does not include hidden execution, persistence, or unrelated data access.
    LLM: benign (high) · VirusTotal: · 13 Aug 2026