Skill rating

Apply A-Evolve's agentic evolution methodology to improve AI agent performance across runs. Use when the user wants to diagnose agent failures, generate targeted skills from error patterns, evolve sys

Orchestrate the full metabolic flux analysis pipeline from model loading to phenotype prediction and publication figures. Triggers when the user provides an organism name, BIGG model ID, or custom rea

Plan publishable constraint-based metabolic modelling studies when the user has a broad biological or metabolic-engineering topic but no concrete dataset, organism, model, or hypothesis. Selects feasi

Reference qiskit 2.x patterns for variational quantum machine learning. Covers data-encoding feature maps, variational quantum classifier (VQC) training, variational quantum eigensolver (VQE) for chem

Publication-ready scientific figure design with matplotlib and seaborn. Use when creating journal submission figures with proper formatting, accessibility, and statistical annotations.

Structured scientific hypothesis generation from observations. Use when formulating testable hypotheses, competing explanations, or experimental predictions.

Statistical test selection, assumption checking, and APA-formatted reporting. Use when analyzing experimental results or writing results sections.

Academic manuscript writing with IMRAD structure, citation formatting, and reporting guidelines. Use when drafting or revising research papers.

Systematic literature review methodology including search strategy, screening, and synthesis. Use when conducting literature reviews or writing background sections.

Bioinformatics with Biopython for sequence manipulation, file parsing, BLAST, and phylogenetics. Use when working with DNA/RNA/protein sequences or biological databases.

Best practices for designing reproducible ML experiments. Use when planning ablations, baselines, or controlled experiments.

Best practices for reinforcement learning policy optimization. Use when working on RL agents, PPO, SAC, or reward design.

Structured methodology for comprehensive literature review following PRISMA guidelines. Use during literature search and screening stages.

Statistical methods for combining results across multiple studies. Use when aggregating cross-study or cross-experiment results.

Run Flux Balance Analysis (FBA) and related constraint-based simulations using COBRApy. Covers standard FBA, parsimonious FBA (pFBA), Flux Variability Analysis (FVA), loopless FBA, gene/reaction knock

Best practices for LLM alignment techniques including RLHF, DPO, and instruction tuning. Use when working on alignment or safety.

Best practices for object detection tasks. Use when working on COCO, VOC, or detection architectures like YOLO and DETR.

Design and run statistical experiments that test the formal problem, proposed methods, theoretical predictions, baselines, and ablations.

Analyze theoretical properties of statistical methods under the formal formulation: identifiability, bias, variance, consistency, asymptotics, coverage, error bounds, robustness, and limitations.

Orchestrate a statistical research pipeline centered on formal problem formulation, method proposal, theoretical analysis, experimental evaluation, comparison, and final result synthesis.

Design statistical methods, baselines, diagnostics, variants, and ablations that directly address a formal problem formulation.

Validate statistical research outputs for formulation quality, method-to- problem alignment, theory presence, experimental evidence, fair comparison, artifact completeness, and final-claim consistency

Multi-GPU and distributed training patterns with PyTorch DDP. Use when scaling training across GPUs.

Best practices for image classification tasks. Use when working on CIFAR, ImageNet, or other classification benchmarks.

Best practices for building robust PyTorch training loops. Use when generating or reviewing ML training code.

Validate a COBRApy genome-scale metabolic model for mass/charge balance, stoichiometric consistency, biomass producibility, dead-end metabolites, thermodynamic loops, and GPR rule formatting. Outputs

Use FP16/BF16 mixed precision to accelerate training and reduce memory. Use when optimizing GPU performance.

Analyse FBA flux distributions to extract biological insights. Covers gene essentiality, phenotypic phase planes, flux sampling, pathway-level aggregation, secretion product prediction, and production

Best practices for language model pretraining and fine-tuning. Use when generating or reviewing NLP training code.

Optimize data loading pipeline to prevent GPU starvation. Use when setting up DataLoader or data preprocessing.

Run the ResearchClaw autonomous research pipeline from a topic, config, and output directory.

Formulate statistical research problems with formal notation, target parameters, assumptions, hypotheses, evaluation criteria, and theory targets.

Build or load a genome-scale metabolic model (GSMM) using COBRApy. Covers loading from BIGG, constructing minimal models from scratch, setting medium constraints, and exporting validated .json model f

Computational chemistry with RDKit for molecular analysis, descriptors, fingerprints, and substructure search. Use when working with SMILES, drug discovery, or cheminformatics tasks.